Data use and misuse has emerged as an area of focus as organizations collect and use data in new and innovative ways, ahead of regulatory and ethical frameworks. The emergence of data use in decision-making has exposed unintended consequences and biases that only push us to replicate the past, not move forward. These misuses are widespread: Facebook’s use of data experiments and selling data to third parties revealed how a lack of ethics could lead to unintended consequences. Examples of biases in data have exposed faulty hiring algorithms. What is appropriate or inappropriate use of data? Does this vary by industry? How do we improve biases and continue to progress? This panel will debate the ethical challenges different industries face in using data with leaders in healthcare, gambling, sports, politics, government, and social media.